Zvidzidzo zvakawanda zvekutanga zvakaratidza kuchinja kune e-fodya kubva pakuputa fodya inzira ine hutano kune vakapindwa muropa nefodya. Ichi ndicho chikonzero e-cigarettes yakawanda inotengeswa senzira dzine utano kune zvigadzirwa zvefodya uye vanoputa vanorayirwa kuti vachinje kune idzi e-cigarettes senhanho yekurega tsika.
Zvisinei, chidzidzo chitsva cheYunivhesiti yeCalifornia, Riverside chinoratidza kuti e-cigarettes inogona kunge isina hutano sezvatiri kuitwa kuti titende. Maererano nekudzidza rakabudiswa mu Journal of Toxics, vatsvakurudzi vakaona kuti kuchinja kubva kune zvigadzirwa zvefodya zvechinyakare kuenda kumidzanga yemagetsi hakubatsiri mukudzoreredza epithelium yemhino kune vanoputa. Vatsvakurudzi vakawana kuti kushandisa e-fodya kwakakonzera zvakafanana gene expression profile molecular alterations sekuputa fodya. Nokudaro, kuchinja kune e-cigarettes haigoni kudzosera epithelium yemhino mukurega kusvuta kune iyo isingasvuti.
Dr. Giovanna Pozuelos, mumwe wevasayendisiti vakaita ongororo iyi, anodaro "Kunyanya, boka reEC rakaratidza kuchinjwa kwemajini ane chekuita nekuwedzera kwekushushikana kweoxidative, immune reaction, uye keratinization, pamwe nehumbowo hwekusashanda zvakanaka kweciliary, uye kuderera kweciliogenesis."
Chikwata chevaongorori chinotungamirwa napurofesa webhayoroji yemasero prue talbot yakashuma kuti mamolecular alterations mu epithelium gene expression profile inokonzerwa nekuchinja kune e-cigarettes inogona kudzivirira kupora kwekufema epithelium yevanhu. Muzvinafundo Talbot nokudaro anotenda kuti kubva pakuputa fodya kuenda kufodya ye-e-fodya zvingangowedzera kukonzeresa kukuvadzwa kwekufema kwepithelial pachinzvimbo chekubatsira pakupora kwayo. Izvi zvinogona kutungamira kune zvakakomba zvirwere zvekufema senge squamous metaplasia.
Sekureva kwaDr. pozuelos squamous metaplasia ndiko kukuvadzwa kunokonzerwa nenyama inotenderera nhengo dzekufema dzakaita sehuro, Thyroid, nemapapu. Zvinokonzerwa nekukuvara kwechepfu kunoenderana nekuputa fodya. Kukuvadzwa uku kunodzoserwa asi, izvi zvinogona kuitika chete kana musvuti asiya tsika.
Maererano nekudzidza vanhu vanoshandisa e-fodya vakave nekuwedzera kwemamorekuru macherechedzo akabatana ne squamous metaplasia. Izvi zvakaratidza kuti panzvimbo ye-e-cigarettes kubatsira mukushandurwa kwe squamous metaplasia vanogona kukanganisa maitiro. Kunyange zvazvo vazhinji vachitenda kuti kuchinja kune e-fodya ndiyo danho rokutanga pakurega kusvuta. Chokwadi kubva muchidzidzo ichi ndechekuti hazvisi. Izvi zvinongodaro nekuti hazvibatsire nekuporeswa kwekukuvara kwehupfu kune matishu ekufema.
Kuti vapedze kudzidza kwavo vatsvakurudzi vepaYunivhesiti yeCalifornia Riverside vakashanda nemapoka matatu evatori vechikamu anoti vasiri kuputa, vanoputa fodya iye zvino uye vaimboputa fodya vanga vachishandisa e-cigarettes echizvarwa chechipiri nguva dzose kwemwedzi mitanhatu yapfuura. Vatsvakurudzi vakabva vaongorora nasal biopsies yakaunganidzwa kubva kune vatori vechikamu muboka rega rega uye vakaenzanisa zvakawanikwa.
Masangano eNational Institutes of Health, FDA Center for Tobacco Products, neNational Institute on Drug Abuse vakatsigira chidzidzo ichi. Yakanzi "Transcriptomic Uchapupu Hwokuti Kuchinja Kubva Kufodya kuenda Kufodya Yemagetsi Hakudzosere Kukuvadzwa kuEpithelium Yekufema," kudzidza uku inowedzera kune ruzivo runowedzera ruzivo iyo zvino inoratidza kuti e-cigarettes haina hutano sezvinoratidzwa mumigwagwa.
