Zvinoenderana ne2 yakazvimiririra ongororo yechidzidzo chekutanga ichaunzwa kuAmerican Heart Association's Scientific Sessions 2022, vanhu vakuru vaishandisa zvemagetsi nicotine yekuburitsa michina, kana fodya yemagetsi, yakanga ine maererano nekusiyana kwehutano hwemwoyo uye yemidziyo yeropa uye yakaita zvakanyanya kuipa pakuongorora kushushikana kwepfungwa pane vanhu vasina kushandisa chero zvigadzirwa zve nicotine. Musangano uyu, uchaitwa mumunhu uye nemagetsi muChicago kubva muna Mbudzi 5-7, 2022, ishanduro huru yepasirese yekufambira mberi kwesainzi, kutsvagisa, uye humbowo-hwakavakirwa kukiriniki yekudzidzira maitiro musainzi yemoyo.
The Cardiac and LUng E-cig Smoking (CLUES) Masayendisiti eChidzidzo achapa zvipfupi zviviri achienzanisa mhedzisiro pakati pevanhu vakaputira, vanhu vakaputa fodya yakajairika, inobvira, uye avo vakazivisa kusadya chero zvigadzirwa zvechikakananda.
Vatsvagiri kubva kuYunivhesiti yeWisconsin vakapedza chidzidzo cheCLUES kubva munaKurume 2019 kusvika Kurume 2022. Chinangwa chayo chaive chekuongorora mhedzisiro yenguva pfupi yekuputa fodya uye kunyungudika muvanopindwa muropa nechikakananda kune vakaenzanirana nevezera ravo vasina kushandisa nicotine chero nzira. Pakati pe395 vatori vechikamu muongororo vaive:
- 164 vanhu vakashuma vachishandisa e-cigarettes chete kweavhareji yemakore 4.1, ne80 muzana vachishandisa muenzaniso wezvino wevaporizers (kureva makore 27.4, 39 muzana vakadzi, 86 muzana yerudzi ruchena);
- vanhu 117 vakasvuta midzanga yenguva dzose, inobvira nguva dzose kweavhareji yamakore 23 (zera rinoreva makore 42.8, 44 muzana yevakadzi, 56 muzana yerudzi rwevachena); uye
- 114 vanhu vakuru vakaratidza kusambofefetera kana kuputa uye avo zvino vaive nemhedzisiro yakaipa weti nicotine (avhareji yemakore 30.8 makore, 50 muzana vakadzi, 69 muzana yerudzi ruchena).
Vatsvagiri vakaongorora BP, pulse rate, uye dhayamita yebrachial artery yeruoko, pamwe nekusiyana kwekurova kwemoyo, kusati kwasvika uye kusvika maminetsi gumi nemashanu mushure mekunge vatori vechikamu vasvuta kana kuputira mumushumo wekutanga (Abstract SU15 - Acute Effects Of Nicotine-ine. Zvinetso Zvechigadzirwa PaMwoyo uye Zvekuzvimirira Basa Pakati peElectroniki Midzanga Vapers, Inopisa Midzanga Yekuputa, Uye Dzidzo: Iyo Clues Chidzidzo). Tsvagiridzo yacho yakazosiyanisa kuverenga kwekutanga-uye-mushure kune avo vakatorwa 3138 kusvika 10 maminetsi vakaparadzana muzvidzidzo zvisina kumbobvira zvaputika kana kuputa.
Vatsvakurudzi vakawana kuti, kana zvichienzaniswa nevanhu vasina kushandisa nicotine, vapers uye avo vaiputa fodya yechinyakare vaive:
- Kuwedzera kukuru kwekurova kwemoyo, zvichireva kuti moyo yavo inorova nekukurumidza Avo vanoputa fodya kana vapeti vaive nekuwedzera kwemoyo kunosvika 4 kurova paminiti (bpm) mushure mekuputa kana kuputa, asi avo vaiti hapana chikakananda chekunwa vaive vasina misiyano mu Mamhanyiro emoyo.
- yakawedzera systolic (nhamba yepamusoro) uye diastolic (nhamba yepasi) BP yeropa yakawedzera kubva pa122/72 mm Hg kusvika pa127/77 mm Hg mushure mekuputa kana kuputa, nepo vanhu vasina kumboshandisa nicotine zvigadzirwa havana kuratidza mutsauko mukuyerwa kweropa. .
Vanhu vakashandisa zvigadzirwa zvine nicotine vakaratidza kudzvanya kwetsinga dzeropa uye zviratidzo zvakanyanya zvekusiyana kwekurova kwemoyo mushure mekusvuta kana kuputika, zvichikurudzira kukurudzirwa kwetsinga dzetsitsi dzemuviri. Iyo inonzwira tsitsi sisitimu yemagetsi inobatsira pakuita kwekurwira-kana-ndege reflex. Kana mumwe munhu ari kushushikana kana kuti ari panjodzi, inotanga kushanda, ichiwedzera kurova kwemwoyo, ichiwedzera chido chemoyo cheokisijeni, uye kukonzera kusashanda zvakanaka kwemadziro emutsinga.
"Pakanga pane maererano nekusiyana kweBP, pulse rate, pulse rate kusiyana, pamwe chete neropa retsinga (constriction) pakarepo mushure mekusvuta kana kupisa," akadaro munyori anotungamirira wekudzidza Matthew C. Tattersall, DO, MS, mubatsiri wepurofesa wemishonga. paYunivhesiti yeWisconsin Chikoro cheMishonga uye Hutano Hwevanhu uye mubatsiri mukuru wezvekudzivirira cardiology paUW Health muMadison, Wisconsin. "Idzi data dzinoratidza njodzi huru yekusiyana kwechirwere chemoyo nguva pfupi mushure mekuputa kana kuputika, uye kunzwira tsitsi tsinga dzetsinga dzinogona kuita chikamu mukukanganisa kwakataurwa mushure mekushandisa fodya yemagetsi uye maminitsi makumi mapfumbamwe gare gare mushure mekuedzwa kwekurovedza muviri."
Ivo vakapindura vamwechete vakasiyaniswa muchiitiko chekuongorora (Abstract SA3142 - Misiyano muTreadmill Exercise Stress Testing Parameters Pakati peElectroniki Cigarette Vapers, Inopisa Midzanga Inoputa, Uye Dzinodzora: Iyo Clues Chidzidzo) kuti vaongorore mashandiro avo mukuyedza kushushikana kwepfungwa, iyo inozivikanwa kufanotaura. migumisiro yechirwere chemwoyo. Treadmill stress bvunzo dzakaitwa dzinenge 90 90 maminetsi mushure mekunge vasvuta kana vap, uye maminetsi makumi mapfumbamwe mushure mekunge avo vaiti hapana chikakananda chazorora.
Munguva uye nekutevera bvunzo yekushushikana, mana emhedzisiro matanho akaunganidzwa uye akaongororwa:
- Metabolic equivalents (METS), chiyero chekuyerwa kwesimba rekurovedza muviri kana kusimba: 1 MET yakaenzana nekugara wakanyarara pakuzorora, nepo kukurumidza kufamba kwakaenzana ne3-4 METS kana 3-4 nguva simba rinoshandiswa nemuviri pakuzorora. Yakaderera METS pabvunzo yekushushikana yakabatana nenjodzi yakawedzera yechirwere chemoyo.
- Chiyero-kudzvanywa kwechigadzirwa chinoreva chiyero chebasa rinoitwa nemoyo panguva yepamusoro-soro yekusimbisa maitiro, kureva basa remoyo. Kuwedzera kukuru kunoratidza kuti mwoyo unokwanisa kushanda nesimba.
- Kureba kwemoyo kunoreva kuyerwa kwekurova kwemoyo wekuzorora vs kwakanyanya kufungidzirwa kurova kwemoyo panguva yekurovedza muviri - nemamwe mazwi, kuchengetedza kwakadii moyo unokwanisa kumhanyisa, nenzvimbo yakakwirira inoratidza kusimba kwemoyo kuri nani.
- Iko 60-second pulse rate recovery ndiyo chiratidzo chekukurumidza kukurumidza kudzoka shure mushure mekurovedza muviri: kukurumidza kudzoka kwemwoyo kunodzoka, zviri nani mamiriro emwoyo wemunhu uye kwenguva refu yehutano hwemwoyo.
Vanhu vaiputa fodya uye vapedhi vakarekodha zvakanyanya kuita kwakaipisisa pamatanho mana ekuita pane avo vaiti hapana chikakananda chekushandisa. Uyezve, kana zvichienzaniswa nevanhu vasina kushandisa nicotine, vanhu vanoputika kana kuputa zuva nezuva:
- yakanga yadzikisira kugona kwekuita maekisesaizi, sezvinoratidzwa nekuderedzwa kweMETS (9.8 yevapers, 9.3 yevanoputa, uye 11.1 kune avo vasina kubatanidzwa).
- pavaiita maekisesaizi pakukwanisa kwavo kukuru, vakawana basa remoyo rakaderera
- vaiva nemoyo wakadzikisira kurova kwemoyo, zvichiratidza kusasimba (87 muzana yevakapindura mavhapesi, 85 muzana yevanoputa, uye 91% yeavo vasina kudaro); uye
- Mushure mekupedza bvunzo yekurovedza muviri, ndakaona kupora zvishoma nezvishoma kwekurova kwemoyo wangu (25.2 bpm yevapers, 22.4 yevanoputa, uye 28.1 kune vanhu vasina kudaro).
"Vanhu vakaputika sezviri pachena vakaita zvakanyanya pane ese mana ekuita maekisesaizi zvichienzaniswa nevaya vasina kumboshandisa chikakananda, kunyangwe mushure mekugadziriswa kwevakadzi, zera, uye dzinza / rudzi," akadaro munyori anotungamira Christina M. Hughey, MD, shamwari mukurapa kwemoyo. UW Health, iyo University yeWisconsin-yakabatana Madison's hutano masisitimu. "Kunyangwe vaive vapfava kwemakore mashoma uye vaive vadiki zvakanyanya, kugona kwevapfap kwakange kwakasiyana zvakanyanya nekwevanhu vaishandisa fodya inobvira."
"Vanhu vakaputira zviri pachena kuti vakaita zvakanyanya pane ese mana maitiro ekusimba zvichienzaniswa nevamwe vavo vasina kushandisa chikakananda, kunyangwe mushure mekugadzirisa hunhu, dzinza, uye zera." "Zvatinoona kubva kuCLUES tsvakurudzo zvinomutsa mibvunzo pamusoro pemigumisiro inogona kuitika yekushandiswa kusingaperi kwemagetsi nicotine delivery systems, kunyanya kune chirwere chemoyo," akadaro CLUES muongorori mukuru James H. Stein, MD, FAHA, mutungamiriri wekudzivirira cardiology paUW Health uye. Robert Turrell Purofesa muCardiovascular Research paYunivhesiti yeWisconsin Chikoro cheMishonga uye Hutano Hwevanhu muMadison. "Hatina kuferefeta mhedzisiro yenguva refu yekuputira, kushandiswa kwayo senzira yekurapa yekuputa, kana kushanda kwayo kana kuchengetedzeka munzvimbo iyoyo." Mhedzisiro iyi, zvisinei, inotyisa sezvo vachiratidza kuti vaping inogona kukwidza njodzi yechirwere chemoyo. Kurudziro yavanhu vanosvuta midzanga inobvira yakafanana: edza kurega kushandisa nicotine nemidziyo yefodya uye tsvaka betsero kuna chiremba wako nenzanga kuti uvandudze mikana yako yokubudirira.”
Iyo CLUES Tsvagiridzo yaive chigadzirwa chakadenha ongororo yekutsvaga. Izvi zvinoreva kuti vanhu vaidzidzwa uye zvinotengeswa zvakaongororwa zvisati zvaitika uye mushure mekushandisa nicotine-ine zvinhu, saka data haigoni kuratidza chikonzero-ne-effect link pakati pekutora zvinhu zvine nicotine uye zviyero zvemwoyo zvakanyorwa. Vatsvakurudzi havana kukwanisa kufananidza zvakananga migumisiro yekusvuta nekuputira sezvo vaputi vakapinda mutsvakurudzo vakanga vakwegura, uye vanga vachishandisa zvinhu zvine nicotine kwemakore akati wandei (avhareji yekushandiswa kwemakore 23 kune vanhu vanoputa fodya yechinyakare vs. 4 makore. kune avo vaishandisa zvemagetsi mudzanga zvinhu), uye vainyanya mukana kubva minoritized ethnicities uye marudzi zvichienzaniswa avo vaped. Nekuti ruzhinji rweavo vaped vakaonekwa sevakuru vachena, zvakawanikwa pamhedzisiro yevaping zvinogona kusashanda kune vanhu vemamwe marudzi nemadzinza.
"Izvi zvakawanikwa zvinobatsira mukuwedzera kwekutsvaga kunoratidza kukuvadzwa kwemoyo pakati pevashandisi vefodya uye vanoputa fodya." Pamusoro pezvo, zvinoratidza kuti njodzi yemwoyo iyi iripo kunyangwe muvanhu vadiki vane nhoroondo pfupi yekushandiswa kwechikakananda,” akadaro Aruni Bhatnagar, Ph.D., FAHA, co-director weAmerican Heart Association's National Institutes of Health/Food and Drug. Administration-inotsigirwa nemari Fodya Center yeRegulatory Sayenzi uye purofesa wemishonga, biochemistry, uye molecular biology paYunivhesiti yeLouisville muLouisville, Kentucky. "Vanhu vanofanirwa kuziva kuti fodya yemagetsi nefodya yechinyakare ine nicotine inopindwa muropa uye zvinhu zvine njodzi zvinogona kukuvadza hurongwa hwemoyo uye hutano hwese."
